Cytokinome profile evaluation in patients with hepatitis C virus infection

doi:10.3748/wjg.v20.i28.9261

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2014; 20(28): 9261-9269
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9261

Table 1 Differences in the serum levels of pro-inflammatory molecules between patients with either hepatitis C virus orliver cirrhosis and the healthy controls

	Controls vs HCV	Controls vs LC
IL-1α	a↑	b↑
IL-1β	b↑	b↑
IL-2R	a↑	b↑
IL-6	b↑	b↑
IL-8	b↑	b↑
CXCL1	b↑	b↑
CXCL9	b↑	b↑
CXCL10	b↑	b↑
CXCL12	a↑	a↑
MIF	a↑	b↑
β-NGF	b↑	b↑
HGF		b↑

P values obtained for all significant molecules in chronic hepatitis C virus (HCV) and HCV-related cirrhosis (LC) patients with respect to controls using the nonparametric Mann-Whitney U test. ^aP value < 0.05, ^bP < 0.01, up arrows indicate an increase in patients’ cytokine serum level vs healthy controls. HCV: Hepatitis C virus; LC: Liver cirrhosis; IL: Interleukin; NGF: Nerve growth factor; HGF: Hepatocyte growth factor; MIF: Migration inhibitory factor.

Citation: Capone F, Guerriero E, Colonna G, Maio P, Mangia A, Castello G, Costantini S. Cytokinome profile evaluation in patients with hepatitis C virus infection. World J Gastroenterol 2014; 20(28): 9261-9269
URL: https://www.wjgnet.com/1007-9327/full/v20/i28/9261.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i28.9261