Escherichia coli-host macrophage interactions in the pathogenesis of inflammatory bowel disease

doi:10.3748/wjg.v20.i27.8751

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2014; 20(27): 8751-8763
Published online Jul 21, 2014. doi: 10.3748/wjg.v20.i27.8751

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Figure 1 Model for the development of Crohn’s disease. AIEC: Adherent, invasive Escherichia coli; ATG16L1: Autophagy-related 16-like 1; CARD15/NOD2: Caspase-recruitment domain 15/nucleotide-binding oligomerization domain-containing-2 receptor; IL-23R: Interleukin-23 receptor; IRGM: Immunity-related GTPase M; LPS: Lipopolysaccharide; NCF4: Neutrophil cytosolic factor-4 gene; PRR: Pathogen recognition receptor; ROS: Reactive oxygen species; TLR4: Toll-like receptor 4.

Citation: Tawfik A, Flanagan PK, Campbell BJ. Escherichia coli-host macrophage interactions in the pathogenesis of inflammatory bowel disease. World J Gastroenterol 2014; 20(27): 8751-8763
URL: https://www.wjgnet.com/1007-9327/full/v20/i27/8751.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i27.8751