Hepatitis B surface antigen levels during natural history of chronic hepatitis B: A Chinese perspective study

Table 3 Correlation between hepatitis B s antigen and laboratory parameters in different phases

	IT (n = 108)		IC (n = 161)		ENH (n = 149)		LR (n = 135)		LC (n = 70)
	r	P value	r	P value	r	P value	r	P value	r	P value
Age	0.153	0.144	0.025	0.757	-0.053	0.519	-0.102	0.319	0.254	0.134
HBV-DNA (log10 IU/mL)	0.287	0.003	0.683	< 0.001	0.342	< 0.001	0.156	0.071	0.177	0.143
ALT (U/L)	-0.119	0.107	-0.102	0.198	0.102	0.215	-0.057	0.422	-0.093	0.445
AST (U/L)	0.060	0.535	-0.072	0.161	0.034	0.681	-0.011	0.880	-0.082	0.499

HBV: Hepatitis B virus; IT: Immune tolerance phase; IC: Immune clearance phase; ENH: Hepatitis B e antigen negative hepatitis; LR: Low-replicative; LC: Liver cirrhosis induced by HBV.