Need for infliximab dose intensification in Crohn’s disease and ulcerative colitis

Table 2 Summary of dose intensification

Dose intensification	Ulcerative colitis	Crohn’s disease	P value
	(n = 38)	(n = 59)
Time on infliximab1 [median (interquartile range), mo]	9 (5.2-12.5)	13.1 (8.1-23.3)	0.006
Rate of intensification per patient-month	3.9%	1.4%	0.005
Time to infliximab intensification [median (interquartile range), mo]	6.6 (4.2-9.5)	10.7 (8.9-15.7)	0.005

¹Time on infliximab: Interval of time between the first infliximab induction dose and the first infliximab intensified dose, or for patients who did not require dose intensification time between the initiation of infliximab and either the last follow-up visit or the time of infliximab discontinuation.