Perioperative advantages of modified laparoscopic vs open splenectomy and azygoportal disconnection

Table 5 Perioperative C-reactive protein, interleukin-6, and procalcitonin concentrations of the modified laparoscopic splenectomy and azygoportal disconnection and open splenectomy and azygoportal disconnection groups

Variable	MLSD (n = 44)	OSD (n = 71)	P value
CRP day 0, median (range), mg/L	1.03 (0.02-49.21)	0.96 (0.03-13.32)	0.715
CRP day 1, mean ± SD, mg/L	28.39 ± 16.30	36.86 ± 12.86	0.002
CRP day 3, mean ± SD, mg/L	92.64 ± 53.16	114.06 ± 44.37	0.022
CRP day 7, mean ± SD, mg/L	41.14 ± 27.61	52.49 ± 29.70	0.043
IL-6 day 0, mean ± SD, pg/mL	6.14 ± 5.61	6.60 ± 7.26	0.715
IL-6 day 1, mean ± SD, pg/mL	8.09 ± 6.97	11.78 ± 9.18	0.024
IL-6 day 3, mean ± SD, pg/mL	7.65 ± 6.95	10.84 ± 8.42	0.037
IL-6 day 7, mean ± SD, pg/mL	6.58 ± 5.66	9.83 ± 8.26	0.024
PCT day 0, mean ± SD, ng/mL	0.45 ± 0.25	0.47 ± 0.27	0.722
PCT 1 d, median (range), ng/mL	0.97 (0.36-3.2)	1.96 (0.54-10.08)	< 0.0001
PCT 3 d, median (range), ng/mL	0.795 (0.3-2.67)	1.45 (0.6-4.88)	< 0.0001
PCT 7 d, median (range), ng/mL	0.5 (0.28-4.01)	0.77 (0.38-5.87)	< 0.0001

CRP: C-reactive protein; IL-6: Interleukin-6; MLSD: Modified laparoscopic splenectomy and azygoportal disconnection; OSD: Open splenectomy and azygoportal disconnection; PCT: Procalcitonin; day 0: Day of admission; day 1: Postoperative day 1; day 3: Postoperative day 3; day 7: Postoperative day 7.