Perioperative advantages of modified laparoscopic vs open splenectomy and azygoportal disconnection

Table 4 Postoperative liver and renal functions of the modified laparoscopic splenectomy and azygoportal disconnection and open splenectomy and azygoportal disconnection groups

Variable	MLSD (n = 44)	OSD (n = 71)	P value
AST 1 d, mean ± SD, U/L	57.32 ± 27.89	87.14 ± 135.13	0.152
AST 3 d, mean ± SD, U/L	33.84 ± 22.16	50.86 ± 43.83	0.018
AST 7 d, mean ± SD, U/L	25.66 ± 11.28	33.63 ± 16.32	0.005
ALT 1 d, mean ± SD, U/L	40.14 ± 18.81	61.66 ± 105.43	0.183
ALT 3 d, mean ± SD, U/L	31.93 ± 25.21	46.93 ± 56.60	0.100
ALT 7 d, mean ± SD, U/L	21.14 ± 12.63	29.68 ± 17.36	0.003
BUN 1 d, mean ± SD, mmol/L	5.52 ± 1.76	6.54 ± 2.33	0.014
BUN 3 d, mean ± SD, mmol/L	6.63 ± 2.20	7.33 ± 2.85	0.171
BUN 7 d, mean ± SD, mmol/L	4.76 ± 2.02	5.52 ± 2.21	0.069
CER 1 d, mean ± SD, μmol/L	75.27 ± 16.22	84.99 ± 20.92	0.010
CER 3 d, mean ± SD, μmol/L	59.75 ± 16.64	66.04 ± 19.08	0.074
CER 7 d, mean ± SD, μmol/L	60.88 ± 13.92	60.83 ± 16.17	0.986

ALT: Alanine aminotransferase; AST: Aspartate transaminase; BUN: Blood urea nitrogen; CER: Creatinine; MLSD: Modified laparoscopic splenectomy and azygoportal disconnection; OSD: Open splenectomy and azygoportal disconnection; day 1: Postoperative day 1; day 3: Postoperative day 3; day 7: Postoperative day 7.