Fluoroquinolone-based protocols for eradication of Helicobacter pylori

doi:10.3748/wjg.v20.i27.8947

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Jul 21, 2014 (publication date) through Feb 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2014; 20(27): 8947-8956
Published online Jul 21, 2014. doi: 10.3748/wjg.v20.i27.8947

Table 1 Current recommendations for Helicobacter pylori eradication

Treatment	Region with low clarithromycin prevalence	Region with high clarithromycin prevalence
First line	PPI - clarithromycin - amoxicillin/metronidazole or bismuth quadruple	Bismuth quadruple¹. If not available: non-bismuth quadruple (either sequential or concomitant)
Second line	Bismuth quadruple¹ or PPI - levofloxacin/amoxicillin	PPI - levofloxacin/amoxicillin
Third line	Based on susceptibility testing only. Besides clarithromycin and levofloxacin, rifabutin is another candidate that may be used

¹PPI + tetracyclines + bismuth + metronidazole. PPI: Proton pump inhibitors.

Citation: Rispo A, Capone P, Castiglione F, Pasquale L, Rea M, Caporaso N. Fluoroquinolone-based protocols for eradication of Helicobacter pylori. World J Gastroenterol 2014; 20(27): 8947-8956
URL: https://www.wjgnet.com/1007-9327/full/v20/i27/8947.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i27.8947