Expression of P450 and nuclear receptors in normal and end-stage Chinese livers

Figure 1 Expression of cytochrome P450 enzymes 1 family genes. A: AhR; B: CYP1A2; C: CYP1A2 in 24 paired HCC and peri-HCC tissue from individual patients. The end-stage livers (HCC and corresponding peri-HCC tissue, n = 24, HBV cirrhosis, n = 27, alcoholic cirrhosis, n = 5 and severe cirrhosis, n = 13) and normal donor trimmed livers (n = 35) were collected at the Oriental Liver Transplant Center, Beijing, China. The data are mean ± SE, Significantly different from normal livers, ^aP < 0.05 vs normal liver; HCC different from peri-HCC tissues. AhR: Aryl hydrocarbon receptor; CYP: Cytochrome P450 enzymes; HCC: Hepatocellular carcinoma; HBV: Hepatitis B virus.