Changes in circulating Foxp3+ regulatory T cells and interleukin-17-producing T helper cells during HBV-related acute-on-chronic liver failure

Figure 4 Population of interleukin-17-producing T helper cells as a percentage of total CD4⁺ cells in the peripheral blood mononuclear cells was evaluated by flow cytometry. A: Representative dot plots of intracellular IL-17 and Foxp3 staining in patients with HBV-related acute-on-chronic liver failure (ACHBLF); B: Percentage of IL-17A⁺CD4⁺T cells in total CD4⁺T cells; C: Percentage of FoxP3⁺CD25⁺CD4⁺T cells in total CD4⁺T cells; D: Ratio of Treg cells to Th17 cells. CHB: Chronic hepatitis B. Differences between ACHBLF and HCs or CHB group were analyzed by the Mann-Whitney test. ^aP < 0.05, ^bP < 0.01 vs ACHBLF group.