Drain amylase value as an early predictor of pancreatic fistula after cephalic duodenopancreatectomy

Table 1 Clinical, intraoperative and postoperative characteristics in relation to the occurrence and stage of pancreatic fistula-univariate analysis n (%)

Parameter	Pancreatic fistula			Pvalue
	No1	BPF2	CRPF3	P12	P13	P23
Gender (M/F)	137/101	50/37	44/131
Age	61.1 ± 10.6	60.0 ± 10.4	61.4 ± 8.2	0.518	0.855	0.407
PF	238 (62.3)	87 (22.8)	57 (14.9)	0.0111	0.0111	0.126
Pancreas texture-soft	9 (10.7)	32 (38.0)	43 (51.2)	0.0011	0.0011	0.225
MPD diameter ≤ 3 mm	45 (23.4)	74 (38.5)	73 (38.1)	0.0361	0.059	0.910
Soft/MPD ≤ 3 mm	7/9 (77.8)	31/32 (96.9)	40/43 (93.0)
Surgical procedure
PPDP	133 (46.0)	74 (25.6)	82 (28.4)	0.0021	0.0071	0.653
Whipple	31 (33.6)	35 (38.0)	26 (28.4)	0.739	0.590	0.384
Pathology
Pancreatic ductal adeno Ca	87 (60.0)	33 (22.8)	25 (17.2)	0.0011	0.0011	0.169
Papila Vateri Ca	28 (26.9)	35 (33.6)	41 (39.5)	0.493	0.250	0.639
Common bile duct/duodenal Ca	16 (30.8)	21 (40.4)	15 (28.8)	0.444	0.719	0.572
Other
Blood transfusion (pt’s)	147/238(61.8)	46/87 (52.9)	33/57 (57.9)	0.0151	0.066	0.610
Blood transfusion (mL)	540.0 ± 345.4	560.7 ± 189.0	504.1 ± 340.4	0.759	0.634	0.416
Hospital stay	14.1 ± 9.0	17.7 ± 6.8	34.1 ± 16.3	0.0131	0.0011	0.0011
Mortality	-	2/87 (2.3)	14/57 (24.6)	-	-	0.0011

¹Significant P < 0.05, n/n, mean ± SD. MPD: Main pancreatic duct; PPDP: Pylorus-preserving duodenopancreatectomy.