Outcomes of autologous bone marrow mononuclear cell transplantation in decompensated liver cirrhosis

Table 4 Levels of prothrombin time, prothrombin activity and fibrinogen in the two groups at different time points after transplantation

Function	Group	1 wk	1 mo	3 mo	6 mo	12 mo	24 mo
Prothrombin time (s)1	Control	16.2 ± 2.8	16.3 ± 2.8	15.9 ± 2.8	15.7 ± 2.9	15.5 ± 2.9	15.7 ± 2.3
	BM-MNCs	16.8 ± 2.5	15.5 ± 2.5	14.4 ± 2.3	13.9 ± 2.1	14.0 ± 2.1	14.4 ± 2.1
	P value	0.472	0.311	0.046	0.019	0.051	0.06
Prothrombin activity1	Control	72.5% ± 17.8%	72.0% ± 17.7%	74.4% ± 17.8%	75.9% ± 18.2%	77.4%± 18.2%	75.6% ± 14.6%
	BM-MNCs	68.7% ± 16.0%	77.3% ± 15.7%	84.3% ± 14.3%	87.2% ± 13.3%	86.9% ± 13.5%	84.0% ± 13.6%
	P value	0.472	0.311	0.046	0.019	0.051	0.06
Fibrinogen (g/L)1	Control	1.90 ± 0.58	1.92 ± 0.57	1.89 ± 0.44	1.97 ± 0.40	1.99 ± 0.39	1.93 ± 0.28
	BM-MNCs	1.86 ± 0.55	2.12 ± 0.64	2.28 ± 0.53	2.51 ± 0.55	2.49 ± 0.51	2.11 ± 0.52
	P value	0.857	0.289	0.017	0.001	0.002	0.233

Data are expressed as the mean ± SD.

¹t test. BM-MNCs: Bone marrow mononuclear cells.