Novel diagnostics for aggravating pancreatic fistulas at the acute phase after pancreatectomy

Table 4 Comparison of diagnostic performance of potent factors for clinically relevant postoperative pancreatic fistula

	Odds ratio	95%CI	P value	Sensitivity	Specificity	Positive predictive value	Negative predictive value	Likelihood ratio of positive result	Likelihood ratio of negative result
CRP ≥ 158 mg/L1	4.82	2.37-10.2	< 0.001	0.594	0.767	0.707	0.667	2.552	0.529
CRP elevation ≥ 28.4 mg/L2	11.4	4.35-34.3	< 0.001	0.864	0.643	0.655	0.857	2.418	0.212
Drain amylase ≥ 1918 IU/mL1	3.00	1.57-5.86	0.001	0.636	0.632	0.636	0.632	1.727	0.576
Risk score ≥ 8	12.9	5.13-35.4	< 0.001	0.795	0.768	0.729	0.827	3.427	0.266

¹Values on postoperative day (POD) 3;

²Change from POD 1 to POD 3. P values were analyzed by binomial logistic analyses. CRP: C-reactive protein.