Colonic polyps: Is it useful to characterize them with advanced endoscopy?

Table 1 Pit pattern classification

Kudo et al[8] class	Description	Most likely histology	Neoplastic/non-neoplastic	Treatment
I	Round crypts	Normal mucosa	Non-neoplastic	None
II	Regular wider or stellar crypts	Hyperplastic polyp (also sessile serrated adenomas)	Non-neoplastic	None if rectosigmoid and ≤ 5 mm/endoscopic resection
IIIL	Elongated or roundish crypts	Adenoma	Neoplastic	Endoscopic resection
IIIs	Tubular or roundish pits smaller than the normal crypts	Intramucosal/superficial invasive cancer	Neoplastic	Endoscopic resection
IV	Branch-like or gyrus-like crypts	Adenoma	Neoplastic	Endoscopic resection
Vi	Irregular crypts	Superficial invasive/deep invasive cancer	Neoplastic	Surgery/endoscopic resection in selected cases
Vn	Non-structural crypts	Deep submucosal invasive cancer	Neoplastic	Surgery