Screening of lymph nodes metastasis associated lncRNAs in colorectal cancer patients

Figure 2 Counts of up-regulated and down-regulated long noncoding RNAs. Up-regulated and down-regulated long noncoding RNAs (lncRNAs) varied in different patients when comparing different samples: many lncRNAs were determined to be significantly up-regulated or down-regulated in metastatic lymph nodes (MLN), normal lymph node (NLN) and tumor tissues of colorectal cancer (CRC) in three patients by microarray analysis. The number of differently expressed lncRNAs between NLN and tumor tissue was much larger than those of differently expressed lncRNAs both between MLN and NLN and between MLN and tumor tissue. M: Metastatic lymph nodes; N: Normal lymph nodes; T: Tumor tissue of colorectal cancer.