Metabolomic studies of human gastric cancer: Review

doi:10.3748/wjg.v20.i25.8092

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Gastroenterol. Jul 7, 2014; 20(25): 8092-8101
Published online Jul 7, 2014. doi: 10.3748/wjg.v20.i25.8092

Table 1 Overview of gastric cancer detection and treatment via traditional methods compared with metabolomics

Cancer detection state/stage	Traditional methods	Metabolomics (biomarkers)	Ref.
Diagnosis	Endoscopy, biopsy	Lactic acid, butanedioic acid, malic acid, citric acids, pyruvic acid, 3-hydroxypropionic acid, serine, proline	[91,93,100,101]
Prognosis	Radiotherapy, chemotherapy surgery	Valine, isoleucine, serine, 3-indoxyl sulfate, hippurate, citrate	[96,99,102]
Metastasis	Computed tomography (CT) scanning, endoscopic ultrasonography (EUS), positron emission tomography (PET)	Sarcosine, alanine, proline, serine, myo-inositol, glycerol	[90,91,98,103]
Chemosensitivity of drugs	MTT chemosensitivity assay	1-acyl-lysophosphatidylcholines and polyunsaturated fatty acids	[75,104]

Citation: Jayavelu ND, Bar NS. Metabolomic studies of human gastric cancer: Review. World J Gastroenterol 2014; 20(25): 8092-8101
URL: https://www.wjgnet.com/1007-9327/full/v20/i25/8092.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i25.8092