Liver fibrosis markers in alcoholic liver disease

Table 1 Characteristic of studies concerning alcoholic liver disease

Study	Number of patients	Age (yr)	Alcohol consumption	Exclusion criteria
Rosenberg et al[24] (2004)	64	18-74	No data	Any disorder associated with extrahepatic fibrosis; cardiovascular disease or cancer; advanced cirrhosis; regular consumption of aspirin; hepatocellular carcinoma or drug-induced liver disease
Calès et al[20] (2005)	95	18-74	≥ 50 g/d for the previous 5 yr (mean: 94 g/d ± 50)	Other causes of LD or complicated cirrhosis or received antifibrotic treatment within the previous 6 mo
Naveau et al[4] (2005)	221	47 (SE = 0.7)	at least 50 g/d over the previous year	Concomitant liver disease, HIV antibodies, immune-suppression, hepatic surface antigen, antibodies to HCV, associated severe diseases
Naveau et al[22] (2009)	218	47.1 (SE = 0.7)	≥ 50 g/d during the preceding y (mean 146 g/d, SE = 80 g/d for 17 yr)	Concomitant liver disease, human immunodeficiency virus antibodies, immunosupression
Poynard et al[23] (2012)	218	47 (SD = 10.3)	No data	HIV co-infection

HCV: Hepatitis C virus; LD: Liver disease; HIV: Human immunodeficiency virus.