Novel treatment options for perforations of the upper gastrointestinal tract: Endoscopic vacuum therapy and over-the-scope clips

Table 1 Synopsis of studies reporting endoscopic vacuum therapy for upper gastrointestinal perforations n (%)

Ref.	Year	Overall (n)	Postoperative (n)	Other perforations (n)	Overall success	Complications	Mortality	Stenosis after completed therapy
Ahrens et al[13]	2010	5	5	0	5/5 (100)	0/5 (0)	1/5 (20)1	2/5 (40)
Brangewitz et al[55]	2013	32	30	2	27/32 (84)	0/32 (0)	5/32 (16)	3/32 (9)
Kuehn et al[29]	2012	9	5	4	8/9 (89)	0/9 (0)	1/9 (11)
Schorsch et al[3]	2013	24	17	7	23/24 (96)		1/24 (4)	1/18 (6)
Schniewind et al[54]	2013	17	17	0			2/17 (12)
Wedemeyer et al[56]	2010	8	8	0	7/8 (88)	0/8 (0)	0/8 (0)	1/8 (13)
Weidenhagen et al[30]	2010	6	6	0	6/6 (100)	0/6 (0)	1/6 (17)	1/6 (17)
Overall		101	88	13	76/84 (90)	0/60 (0)	11/101 (11)	8/69 (12)

¹One patient died during dilation of a stenosis after complete healing (aorto-esophageal fistula).