Topic Highlight
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Jun 28, 2014; 20(24): 7686-7695
Published online Jun 28, 2014. doi: 10.3748/wjg.v20.i24.7686
Table 1 Comparison of hepatitis B surface antigen kinetic between interferon and nucleos(t)ide analogues
Interferon vs NAHBeAg statusMean decline of HBsAg (log IU/mL) at week 48Ref.
Peginterferon alfa-2a + lamivudine vs lamivudineHBeAg (-) patients0.71 vs 0.02P < 0.001[13]
Peginterferon alfa-2a vs lamivudine alone0.67 vs 0.02P < 0.001
Peginterferon vs entecavirHBeAg (+) patients0.94 vs 0.38P = 0.07[26]
HBeAg (-) patients0.56 vs -0.10P < 0.001