HBeAg negative variants and their role in the natural history of chronic hepatitis B virus infection

Table 1 Epidemiology of precore and basal core promoter variants and their correlation with hepatitis B virus genotype distribution[15-18,30]

Genotype	Region	Precore variant	Basal core promoter variant
B, C	East and South East Asia	Yes	Yes
A	Northern Europe, North America, Central Africa	No	Yes
D	Southern Europe, Middle East, Indian subcontinent	Yes	No
E	West and Sub-Saharan Africa	Yes	No
F	Indian Population of Central and South America	No	No