Inhibitory effects of rapamycin on the different stages of hepatic fibrosis

Figure 2 Transforming growth factor β1 and platelet-derived growth factor mRNA expression was assessed by polymerase chain reaction analysis. A: Transforming growth factor β1 (TGFβ1); B: Platelet-derived growth factor (PDGF). BDL: Bile duct ligation; Rapa: Rapamycin; Rapa⁺: Rat administered rapamycin for 28 d starting the 14^th day after BDL; Rapa⁺⁺: Rat administered rapamycin treatment for 28 d starting the 1^st day after BDL; GAPDH: Glyceraldehyde 3-phosphate dehydrogenase. ^aP < 0.05 vs other group; ^cP < 0.05 vs BDL⁺/Rapa⁺⁺ group.