Protective effect of bone marrow mesenchymal stem cells in intestinal barrier permeability after heterotopic intestinal transplantation

Figure 5 Occludin and zona occludens-1 mRNA expression after heterotopic intestinal transplantation. Occludin and zona occludens (ZO)-1 mRNA expression was significantly lower in group B than in group A (^aP < 0.05 vs group B at day 5: 0.3135 ± 0.0168 vs 0.7011 ± 0.0128; ^aP < 0.05 vs group B at day 7: 0.2101 ± 0.0279 vs 0.5345 ± 0.0136). Occludin and ZO-1 mRNA expression was significantly higher in group C than in group B at day 5 (^aP < 0.05 vs group B at day 7: 0.3860 ± 0.0254 vs 0.1673 ± 0.0369; ^aP < 0.05 vs group B at day 5: 0.5727 ± 0.0419 vs 0.3598 ± 0.0242). A: Group A (non-rejection); B: Group B (rejection); C: Group C (bone marrow mesenchymal stem cells therapy). β-actin was used as the loading control. Values shown are the mean ± SD.