Cronkhite-Canada syndrome: Report of six cases and review of literature

Table 1 Therapy and prognosis for all six patients

Patient	Therapy	Prognosis
M/65	Prednisone, PPI, antibiotics, 5-ASA, Lactobacillus, and nutrition nutritional therapy	Diarrhea, skin hyperpigmentation, atrophic nail remission
F/54	Prednisone, nutritional therapy, and antacid drugs	Diarrhea, appetite, atrophic nail remission Gastrointestinal polyps unchanged 1 mo later
M/54	Prednisone, antibiotics, nutritional therapy, antacid drugs, and polypectomy	Diarrhea, abdominal pain remission Gastrointestinal polyps unchanged 1 mo later
F/69	Prednisone, nutritional therapy, and antacid drugs	Diarrhea, skin hyperpigmentation, atrophic nail remission, gastrointestinal polyps reduced 1 yr later
F/24	Albendazole , antibiotics and sulfasalazine	Diarrhea, appetite remission, atrophic nail, and alopecia aggravated
M/62	Prednisone, albendazole, antibiotics, sulfasalazine and polypectomy	Diarrhea, atrophic nail and polyps resolved 8 wk later Prednisone was discontinued after 3 yr, and all symptoms relapsed

5-ASA: 5-aminosalicylic acid.