Mesothelin promotes cell proliferation in the remodeling of neonatal rat pancreas

Figure 3 Adenovirus-mediated downregulation of mesothelin in neonatal rat pancreas. Real-time polymerase chain reaction (PCR) (A) and western blotting (B) assays show the relative expression of mesothelin in the day 7, day 14 and 1 mo rat pancreas after adenovirus injection. Body weight (C) and blood glucose (D) in the sham, Ad-EGFP and Ad-mesothelin did not differ between the three groups. The qPCR data are normalized to18S. Values are expressed as the mean ± SD from three experiments (n = 3 litters; 18 animals). ^aP < 0.05 vs Ad-EGFP group.