Multispecies probiotic protects gut barrier function in experimental models

Figure 5 Effect of Lactibiane Tolerance^® treatment on toll-like receptor-4 immunoreactivity in colonic sections of control or stressed (water avoidance stress) mice. The Toll-like receptor-4 (TLR-4) staining intensity was increased in colonic epithelial cells in stressed mice (arrows). Lactibiane Tolerance (LT) treatment decreased TLR-4 expression in stressed animals. Statistical significance for differences was evaluated with the two-way Anova analysis followed by the Bonferroni post-test set at P < 0.05: ^aP < 0.05 vs control group; ^cP < 0.05 vs water avoidance stress (WAS) group.