Multispecies probiotic protects gut barrier function in experimental models

Figure 4 Effect of Lactibiane Tolerance^® treatment. A: On stress-induced visceral hypersensitivity; B: On stress-induced intestinal hyperpermeability; C: On stress-induced occludin expression. A treatment with Lactibiane Tolerance (LT) given 15 d before and for 4 d during water avoidance stress (WAS) prevented stress-induced hypersensitivity in mice as well as stress-induced hyperpermeability and the defect in occludin expression. Statistical significance for differences was evaluated with the one-way Anova analysis (hyperpermeability) or two-way Anova analysis (hypersensitivity) followed by the Bonferroni post-test set at P < 0.05: ^dP < 0.01 vs control group; ^bP < 0.01 vs WAS group.