Multispecies probiotic protects gut barrier function in experimental models

Figure 3 Effect of the Lactibiane Tolerance^® strain combination on the changes in T84 monolayer permeability induced by intestinal bowel syndrome colonic biopsy conditioned medium. Experiments were performed in duplicate and data were normalized to the culture medium control. A: Variations in permeability induced by each conditioned medium: Conditioned medium of intestinal bowel syndrome patient colonic biopsies (IBS-CM) “A” and “B” were obtained from patients with a constipation form of IBS and “C”,” D” and “E” with a diarrhea form; B: Mean of permeability variations induced by the five conditioned media; C: Statistical significance for differences between IBS-CM and IBS-CM + LT were evaluated with the Student’s t test set at P < 0.05 and is displayed as ^bP < 0.01 (IBS-CM vs IBS-CM + LT). LT: Lactibiane Tolerance.