Risk factors and therapeutic results of early local recurrence after transcatheter arterial chemoembolization

Table 2 Univariate and multivariate analysis of factors significantly predictive of early local recurrence after achieving a complete response

Variable	Univariate analysis			Multivariate analysis
	OR	95%CI	P value	OR	95%CI	P value
Age (≥ 65 yr)	0.489	0.233-1.026	0.058	-	-	-
Sex (female)	2.239	1.028-4.876	0.042	1.969	0.704-5.507	0.197
Tumor number, multiple	2.614	1.203-5.680	0.015	2.171	0.784-6.012	0.136
Tumor size (cm)
2-5	3.107	1.318-7.324	0.010	3.911	1.344-11.383	0.012
> 5	9.000	2.401-33.738	0.001	5.218	1.056-25.767	0.043
Child-Pugh score (≥ 8)	2.773	0.785-9.788	0.113	-	-	-
Decompensated LC	0.830	0.385-1.788	0.634	-	-	-
Gelfoam or PVA use	1.487	0.662-3.340	0.336	-	-	-
Bilirubin (> 2.0 mg/dL)	3.351	0.623-18.030	0.159	-	-	-
Albumin (< 3.5 mg/dL)	1.550	0.732-3.284	0.252	-	-	-
Post-CR AFP (> 20 ng/mL)	2.362	1.023-5.456	0.044	3.464	1.262-9.507	0.016
Lipiodol uptake (non-compact)	9.342	2.916-29.929	< 0.001	9.092	2.537-32.508	0.001
TACE number to CR (≥ 2)	2.765	1.105-6.924	0.030	2.029	0.715-5.756	0.715

AFP: α-fetoprotein; CR: Complete response; OR: Odds ratio; LC: Liver cirrhosis; PVA: Polyvinyl alcohol; TACE: Transcatheter arterial chemoembolization; PVT: Portal vein thrombosis.