Role of the Na+/K+/2Cl- cotransporter NKCC1 in cell cycle progression in human esophageal squamous cell carcinoma

Table 2 Twenty genes displaying the highest change in expression levels in Na⁺/K⁺/2Cl^- cotransporter 1 depleted KYSE170 cells

Gene Symbol	Gene ID	Gene Name	Fold Change
Upregulated Genes
C18orf34	NM_001105528	Chromosome 18 open reading frame 34	155.49
KCNA6	NM_002235	Potassium voltage-gated channel, shaker-related subfamily, member 6	140.4
CCDC147	NM_001008723	Coiled-coil domain containing 147	105.98
C20orf202	NM_001009612	Chromosome 20 open reading frame 202	86.17
A1CF	NM_138933	APOBEC1 complementation factor	70.98
SH3GL2	NM_003026	SH3-domain GRB2-like 2	70.93
PTGFR	NM_001039585	Prostaglandin F receptor (FP)	66.99
NDN	NM_002487	Necdin homolog (mouse)	66.45
INPP5D	NM_001017915	Inositol polyphosphate-5-phosphatase, 145 kDa	52.83
CYP2E1	NM_000773	Cytochrome P450, family 2, subfamily E, polypeptide 1	52.44
AGBL3	NM_178563	ATP/GTP binding protein-like 3	50.88
UBTFL1	NM_001143975	Upstream binding transcription factor, RNA polymerase I-like 1	47.88
PADI2	NM_007365	Peptidyl arginine deiminase, type II	46.83
CCR1	NM_001295	Chemokine (C-C motif) receptor 1	44.86
ARC	NM_015193	Activity-regulated cytoskeleton-associated protein	44.41
COLEC10	NM_006438	Homo sapiens collectin sub-family member 10 (C-type lectin)	44.28
DNAH6	NM_001370	Dynein, axonemal, heavy chain 6	41.96
BOLL	NM_033030	Bol, boule-like (Drosophila)	41.31
CORO2B	NM_006091	Coronin, actin binding protein, 2B	41.04
MUC7	NM_152291	Mucin 7, secreted	36.97
Downregulated Genes
NPFFR1	NM_022146	Neuropeptide FF receptor 1	-54.97
LRRFIP1	NM_001137550	Leucine rich repeat (in FLII) interacting protein 1	-44.72
PPIL6	NM_173672	Peptidylprolyl isomerase (cyclophilin)-like 6	-44.46
CRHR2	NM_001883	Corticotropin releasing hormone receptor 2	-39.78
CMTM2	NM_144673	CKLF-like MARVEL transmembrane domain containing 2	-39.62
C5	NM_001735	Complement component 5	-39.13
KCNMA1	NM_001014797	Potassium large conductance calcium-activated channel, subfamily M, alpha member 1	-38.59
HESX1	NM_003865	HESX homeobox 1	-33.03
SLC22A2	NM_003058	Solute carrier family 22 (organic cation transporter), member 2	-32.49
WNT8B	NM_003393	Wingless-type MMTV integration site family, member 8B	-32.17
GRIA1	NM_000827	Glutamate receptor, ionotropic, AMPA 1	-31.27
ZNF367	NM_153695	Zinc finger protein 367	-30.04
GPR128	NM_032787	G protein-coupled receptor 128	-29.88
SLC12A2	NM_001046	Solute carrier family 12 (sodium/potassium/chloride transporters), member 2	-28.92
KCNG2	NM_012283	Potassium voltage-gated channel, subfamily G, member 2	-28.3
ECT2L	NM_001077706	Epithelial cell transforming sequence 2 oncogene-like	-27
ERMN	NM_020711	Ermin, ERM-like protein	-26.61
DPP10	NM_020868	Dipeptidyl-peptidase 10 (non-functional)	-26.58
TSPAN7	NM_004615	Tetraspanin 7	-25.54
APOA1	NM_000039	Apolipoprotein A-I	-25.21