Novel method for extracting exosomes of hepatocellular carcinoma cells

Figure 1 Characterization of the exosomes of Huh-7 cells extracted by two methods. Electron micrographs of exosomes isolated from Huh-7 cells in serum-free concentrated culture medium by the traditional method (A) and the new extraction method based on a nanomaterial (B). Negative-stained images show exosomes with a smooth, saucer-like morphology. The sizes are between 30-100 nm. The scale bar is 50 nm. Direct Mag: 100000 ×, HV = 80.0 kV.