Investigation of cholecystokinin receptors in the human lower esophageal sphincter

Figure 4 Representative competitive inhibition curves of the binding of ³H- cholecystokinin-8S to membrane proteins isolated from the human sling (A) and clasp (B) fibers. The antagonists used were CR-1409 [selective for cholecystokinin (CCK)-A receptors] and CR-2945 (CCK-B receptors). Binding is expressed as the percentage of radioactivity specifically bound in the absence of antagonists.