Topic Highlight
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Jun 7, 2014; 20(21): 6448-6456
Published online Jun 7, 2014. doi: 10.3748/wjg.v20.i21.6448
Figure 2
Figure 2 Mechanism of Epstein-Barr virus infection in B lymphocytes. Epstein-Barr virus (EBV) envelope glycoproteins gp350/220 bind to B lymphocyte receptors CD21 and/or CD35. Simultaneously, viral glycoprotein gp42 interacts with HLA II on the B cell membrane to trigger the core fusion complex, enabling EBV entry into the B cell.