Liver resection in hepatitis B related-hepatocellular carcinoma: Clinical outcomes and safety in elderly patients

doi:10.3748/wjg.v20.i21.6620

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jun 7, 2014; 20(21): 6620-6625
Published online Jun 7, 2014. doi: 10.3748/wjg.v20.i21.6620

Table 1 Clinical characteristics in elderly and younger hepatitis B virus-related hepatocellular carcinoma patients n (%)

Clinicalcharacteristics	Elderly (≥ 65 yr)(n = 207)	Younger (< 65 yr)(n = 1336)	P value
Age (yr), median (IQR)	68 (66-73)	47 (40-56)	< 0.001
Male	166 (80.2)	1128 (84.4)	0.123
Body mass index (kg/m²), mean (SD)	22.8 (2.9)	22.9 (2.9)	0.899
HBsAg(+)	123 (59.4)	1127 (84.4)	< 0.001
HBeAg(+)	10 (4.8)	236 (17.7)	< 0.001
HBV DNA (+)	50 (24.2)	433 (32.4)	0.017
AST (U/L), median (IQR)	35 (25-55)	40 (29-64)	0.001
ALT (U/L), median (IQR)	34 (24-49)	40 (29-60)	< 0.001
White Blood Cells (10⁹/L), median (IQR)	5.34 (4.18-6.67)	5.37 (4.25-6.63)	0.656
Hemoglobin (g/L), median (IQR)	134 (122-144)	143 (130-153)	< 0.001
Platelets (10⁹/L), median (IQR)	136 (92-185)	130 (92-183)	0.999
Portal hypertension	52 (25.1)	376 (28.1)	0.366

HCC: Hepatocellular carcinoma; HBV: Hepatitis B virus; HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen; HBV-DNA: Positive indicated by hepatitis B virus DNA > 2000U/mL; IQR: Interquartile range; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.

Citation: Wang HQ, Yang J, Yan LN, Zhang XW, Yang JY. Liver resection in hepatitis B related-hepatocellular carcinoma: Clinical outcomes and safety in elderly patients. World J Gastroenterol 2014; 20(21): 6620-6625
URL: https://www.wjgnet.com/1007-9327/full/v20/i21/6620.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i21.6620