Colon cancer-associated B2 Escherichia coli colonize gut mucosa and promote cell proliferation

Table 4 Distribution of Escherichia coli strains producing various cyclomodulins according to phylogroups and specimen origins n (%)

Phylogoups		E. coli strains exhibiting cyclomodulin-encoding genes
		pks	cnf	cdt	cif
Colon cancer-associated E. coli strains (n = 88)1	A (n = 20)	0 (0)	0 (0)	0 (0)	2 (2)
	B1 (n = 14)	0 (0)	1 (1)	1 (1)	1 (1)
	B2 (n = 38)	23 (26)	16 (18)	4 (11)	0 (0)
	D (n = 16)	0 (0)	1 (1)	1 (1)	0 (0)
Diverticulosis-associated E. coli strains (n = 46)2	A (n = 17)	0 (0)	0 (0)	0 (0)	0 (0)
	B1 (n = 3)	0 (0)	0 (0)	0 (0)	0 (0)
	B2 (n = 15)	6 (13)	4 (9)	0 (0)	0 (0)
	D (n = 11)	0 (0)	0 (0)	0 (0)	0 (0)

¹Isolated from 48 colon cancer patients;

²Isolated from 33 patients with diverticulosis. E. coli: Escherichia coli.