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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. May 28, 2014; 20(20): 6329-6335
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6329
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6329
Table 3 Hypermethylation status of SFRP2 and WIF-1 in fecal DNA samples n (%)
| Group | Case | Hypermethylated genes | ||
| SFRP2 | WIF-1 | SFRP2+WIF-1 | ||
| CRC | 48 | 27 (56.3) | 29 (60.4) | 39 (81.3) |
| Dukes A-B | 27 | 15 (55.6) | 18 (66.7) | 22 (81.5) |
| Dukes A | 7 | 5 (71.4) | 4 (57.1) | 6 (85.7) |
| Dukes B | 20 | 10 (50.0) | 14 (70.0) | 16 (80.0) |
| Dukes C-D | 21 | 12 (57.1) | 11 (52.4) | 17 (81.0) |
| Dukes C | 14 | 8 (57.1) | 7 (50.0) | 10 (71.4) |
| Dukes D | 7 | 4 (57.1) | 4 (57.1) | 7 (100) |
| Adenoma | 35 | 18 (51.4) | 16 (45.7) | 23 (65.7) |
| Advanced | 15 | 9 (60.0) | 8 (53.3) | 12 (80.0) |
| Non-advanced | 20 | 8 (40.0) | 7 (35.0) | 11 (55.0) |
| Hyperplastic polyp | 32 | 4 (12.5) | 6 (18.7) | 8 (25.0) |
| Normal control | 30 | 0 (0) | 1 (3.3) | 1 (3.3) |
- Citation: Zhang H, Zhu YQ, Wu YQ, Zhang P, Qi J. Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancer. World J Gastroenterol 2014; 20(20): 6329-6335
- URL: https://www.wjgnet.com/1007-9327/full/v20/i20/6329.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i20.6329