Management of chronic hepatitis B infection: Current treatment guidelines, challenges, and new developments

doi:10.3748/wjg.v20.i20.6262

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 20, Issue 20

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (16624)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-2) series, Tables (1-9) series.

Item

Count

PDF

1429

WORD

421

HTML

11940

Figures (1-2)

359

Tables (1-9)

243

Sum=14392

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1164

Download

1068

Sum=2232

May 28, 2014 (publication date) through Jan 23, 2025

Times Cited of This Article

Times Cited (107)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Gastroenterol. May 28, 2014; 20(20): 6262-6278
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6262

Table 7 Treatment endpoints in clinical use

Treatment	Description
Biochemical	Normalization of serum ALT
Virological
HBeAg-positive	Loss of HBeAg, Anti-HBe antibodies, serum HBV-DNA < 2000 IU/mL
HBeAg-negative	Serum HBV-DNA < 2000 IU/mL
Complete	Biochemical and virological response with loss of serum HBsAg
Histological	Decrease in necroinflammatory activity without worsening in fibrosis

ALT: Alanine transaminase; HBV: Hepatitis B virus; HBeAg: Hepatitis B e antigen; HBsAg: Hepatitis B surface antigen.

Citation: Tang CM, Yau TO, Yu J. Management of chronic hepatitis B infection: Current treatment guidelines, challenges, and new developments. World J Gastroenterol 2014; 20(20): 6262-6278
URL: https://www.wjgnet.com/1007-9327/full/v20/i20/6262.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i20.6262