Management of chronic hepatitis B infection: Current treatment guidelines, challenges, and new developments

doi:10.3748/wjg.v20.i20.6262

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May 28, 2014 (publication date) through Jan 23, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 28, 2014; 20(20): 6262-6278
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6262

Table 4 Recommendations for the use of pegylated interferon as initial antiviral therapy

HBV genotype	General recommendations for HBeAg positive patients
A	Either high ALT (≥ 2 × ULN) or low HBV DNA levels (< 9 log₁₀ copies/mL)
B and C	Both high ALT (≥ 2 × ULN) and low HBV DNA levels (< 9 log₁₀ copies/mL)
D	Not recommended

HBV: Hepatitis B virus; HBeAg: Hepatitis B e antigen; ALT: Alanine transaminase; ULN: Upper limit of normal.

Citation: Tang CM, Yau TO, Yu J. Management of chronic hepatitis B infection: Current treatment guidelines, challenges, and new developments. World J Gastroenterol 2014; 20(20): 6262-6278
URL: https://www.wjgnet.com/1007-9327/full/v20/i20/6262.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i20.6262