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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. May 28, 2014; 20(20): 5973-5986
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.5973
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.5973
Table 1 Examples of dysregulated miRNAs in hepatitis B virus-infected or hepatitis B virus-related hepatocellular carcinoma patients at various locations as compared to healthy or non-tumorous controls
Locations | Regulation1 | List of miRNAs |
HBV serum/plasma | Up | miR-375[64], miR-92a[64], miR-10a[64], miR-223[64], miR-423[64], miR-23b/a[64], miR-342-3p[64], miR-99a[64,75], miR-122a[64], miR-125b[64,75], miR-150[64], let-7c[64], miR-100[75], miR-122[75], miR-122*[75], miR-192[75], miR-192*[75], miR-193b[75], miR-194[75], miR-215[75], miR-365[75], miR-455-5p[75], miR-455-3p[75], miR-483-3p[75], miR-885-5p[75], miR-1247[75] |
Down | - | |
HBV-HCC serum/plasma | Up | miR-122[81], miR-192[81], miR-194[81], miR-21[81], miR-23b[81], miR-801[81] |
Down | miR-223[81], miR-132[104] | |
Dysplastic nodules | Up | miR-224[73] |
Down | miR-145[73], miR-199b[73] | |
HCC tumours | Up | miR-224[74], miR-27a[112], miR-501[110] |
Down | miR-422b[74], miR-122a[74], miR-132[104], miR-148a[108], let-7a[107], miR-101[102] |
- Citation: Tan YLJ, Chen WN. MicroRNAs as therapeutic strategy for hepatitis B virus-associated hepatocellular carcinoma: Current status and future prospects. World J Gastroenterol 2014; 20(20): 5973-5986
- URL: https://www.wjgnet.com/1007-9327/full/v20/i20/5973.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i20.5973