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©2014 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 14, 2014; 20(2): 460-467
Published online Jan 14, 2014. doi: 10.3748/wjg.v20.i2.460
Published online Jan 14, 2014. doi: 10.3748/wjg.v20.i2.460
Region | Mutations related to severe liver diseases | P value | Ref. | |
PreC/C | PreC | W28* [HCC 12/35 (34.3%) vs LC+ CH + C 5/35 (14.3%)] | 0.093 | Kim et al[11] |
C | P5H/L/T [HCC 5/35 (14.3%) vs LC + CH + C 0/35 (0%)] | 0.020 | Kim et al[11] | |
E83D [HCC 4/35 (11.4%) vs LC + CH + C 0/35 (0%)] | 0.039 | Kim et al[11] | ||
I97F/L [HCC 13/35 (37.1%) vs LC + CH + C 4/35 (11.4%)] | 0.024 | Kim et al[11] | ||
L100I [HCC 6/35 (17.1%) vs LC + CH + C 1/35 (2.9%)] | 0.046 | Kim et al[11] | ||
Q182K/* [HCC 4/35 (11.4%) vs LC + CH + C 0/35 (0%)] | 0.039 | Kim et al[11] | ||
PreS | preS1 | W4P/R [HCC 13/96 (13.5%) vs CH 0/32 (13.2%)] | 0.028 | Lee et al[9] |
PreS1 start deletion [HCC 9/40 (22.5%) vs C 1/38 (2.6%)] | 0.048 | Mun et al[16] | ||
preS2 | F141L [HCC 26/99 (26.3%) vs LC 2/52 (3.8%)] | 0.001 | Mun et al[15] | |
PreS2 deletion [HCC 35/99 (35.4%) vs CH 6/45 (13.3%)] | 0.020 | Mun et al[15] | ||
S | S | W182* [HCC + LC 56/176 (31.8%) vs CH + C 17/99 (17.2%)] | 0.010 | Lee et al[12] |
X | X | V5M/L [HCC 30/60 (50.0%) vs LC 11/42 (26.2%)] | 0.024 | Kim et al[22] |
P38S [HCC 13/60 (21.7%) vs C 2/41 (4.9%)] | 0.023 | Kim et al[22] | ||
H94Y [HCC 24/60 (40.0%) vs C 2/41 (4.9%)] | < 0.001 | Kim et al[22] | ||
I127T/N [HCC 22/60 (36.7%) vs CH 6/41 (14.6%)] | 0.023 | Kim et al[22] | ||
KV130MI [HCC 52/60 (86.7%) vs CH 25/41 (61.0%)] | 0.004 | Kim et al[22] |
- Citation: Kim BJ. Hepatitis B virus mutations related to liver disease progression of Korean patients. World J Gastroenterol 2014; 20(2): 460-467
- URL: https://www.wjgnet.com/1007-9327/full/v20/i2/460.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i2.460