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World J Gastroenterol. Jan 14, 2014; 20(2): 346-362
Published online Jan 14, 2014. doi: 10.3748/wjg.v20.i2.346
Published online Jan 14, 2014. doi: 10.3748/wjg.v20.i2.346
Intervention | Study design | Sample size | Outcome | Ref. |
Hypnotherapy | Pre- and post-assessment | 23 | Normalized hypersensitivity pain threshold in hypersensitive group (P = 0.04) after 12 wk of treatment, no significant change in hyposensitive and normosensitive groups | [154] |
Hypnotherapy | Randomized controlled trial in children with functional abdominal pain or IBS | 53 | Significant reduction in pain scores in hypnotherapy group (P < 0.001) compared to standard medical therapy at 1-yr after intervention | [159] |
Hypnotherapy | Questionnaire | 83 | 69% of patients were either satisfied or very satisfied with hypnotherapy following 12 wk intervention, overall improvement in quality of life and GI symptoms | [160] |
Hypnotherapy | Randomized, placebo-controlled study | 138 in two studies (90 and 48) | Significant reduction in IBS symptoms in hypnotherapy groups (P < 0.05) compared to supportive therapy after 3 mo of intervention | [161] |
Hypnotherapy | Randomized, placebo-controlled study | 90 | Significant improvement in overall IBS symptoms in gut-directed hypnotherapy and medical treatment group compared to medical treatment group alone (P = 0.046) after 12 wk; improvement remained up to 12 mo after intervention in hypnotherapy group (P = 0.004) compared to medical treatment alone | [162] |
Hypnotherapy | Pre- and post-assessment | 75 | Group hypnotherapy decreased symptom severity significantly (P < 0.01) at 3, 6, and 12 mo post-intervention | [163] |
Hypnotherapy | Retrospective analysis | 208 | Significantly higher use of hypnotherapy (P < 0.001) by initial responders vs non-responders at 2-7 yr follow-up, in total 87% of participants reported hypnotherapy to be useful | [164] |
Cognitive behavior therapy | Randomized-comparator-controlled study in patients with functional bowel disorders | 431 | CBT was more effective than education (P = 0.0001) and desipramine was more effective than placebo (P = 0.01) after 12 wk of treatment as assessed by treatment satisfaction | [170] |
Cognitive behavior therapy | Randomized, placebo-controlled study in patients with functional bowel disorders | 397 | No significant differences between treatment arms for desipramine, cognitive behavior therapy, and placebo groups | [171] |
Cognitive behavior therapy and mindfulness training | Randomized controlled trial | 195 | Internet-delivered cognitive behavior therapy resulted in adequate relief of IBS symptoms that was significant compared to internet-delivered stress management at 6 mo follow-up (P = 0.004) | [173] |
Cognitive behavior therapy | Randomized controlled trial | 149 | Significant reduction in symptom severity scores in CBT plus mebeverine group compared to mebeverine alone at post-treatment and 3, 6, and 12 mo follow-up (regression P = 0.001) | [174] |
Psychotherapy [cognitive behavior therapy] | Randomized controlled trial | 50 | Rome-II scores significantly decreased (P = 0.001) in patients receiving CBT in conjunction with standard medical care compared to standard medical care alone after 2 mo intervention | [175] |
Cognitive behavior therapy | Randomized controlled trial | 28 | Psychosocial functioning was significantly improved (P = 0.004) in patients receiving CBT in addition to standard medical care compare to standard medical care alone at 3 mo follow-up | [176] |
Cognitive behavior therapy | Randomized controlled trial | 76 | Cognitive behavior therapy presented with significant improvements compared to stress management and attention control groups in reducing visceral sensitivity (P < 0.0001) compared to baseline at 3 mo follow-up | [177] |
Cognitive behavior therapy | Randomized, placebo-controlled study | 85 | Internet delivered CBT reduced several IBS symptom parameters (total pain, diarrhea, bloating primary symptoms all P < 0.001) after 10 wk of intervention compared to discussion board control group; quality of life and visceral sensitivity were also significantly improved (P < 0.001) after 3 mo follow up | [179] |
Mindfulness training | Randomized controlled trial | 75 | Women in mindfulness training group showed significant reduction (P = 0.006) in IBS symptom severity compared to support control group after 8 wk of intervention which remained significant at 3 mo follow-up (P = 0.001) | [180] |
Cognitive behavior therapy | Retrospective analysis | 75 | Long-term follow-up after 15-18 mo of original intervention resulted in lasting significant reductions in visceral sensitivity (P < 0.05), increase in quality of life (P < 0.05), and gastrointestinal symptoms (P < 0.05) | [181] |
- Citation: Grundmann O, Yoon SL. Complementary and alternative medicines in irritable bowel syndrome: An integrative view. World J Gastroenterol 2014; 20(2): 346-362
- URL: https://www.wjgnet.com/1007-9327/full/v20/i2/346.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i2.346