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World J Gastroenterol. May 21, 2014; 20(19): 5737-5745
Published online May 21, 2014. doi: 10.3748/wjg.v20.i19.5737
Published online May 21, 2014. doi: 10.3748/wjg.v20.i19.5737
Table 1 Hemostasis changes in chronic liver disease patients
Factors favoring anticoagulant state | Factors favoring prothrombotic state |
Thrombocytopenia (decreased thrombopoietin, splenic sequestration) | Decreased liver synthesis of antithrombin III, protein C, protein S |
Thrombocytopathy (impaired platelet function) | Elevated von Willebrand factor levels |
Vitamin K deficiency | Increased factor VIII levels |
Decreased synthesis of coagulation factors including Factor II, VII, IX, X, V, fibrinogen | Genetic predispositions like Factor V Leiden |
Reduced clearance of tissue plasminogen activator |
- Citation: Aggarwal A, Puri K, Liangpunsakul S. Deep vein thrombosis and pulmonary embolism in cirrhotic patients: Systematic review. World J Gastroenterol 2014; 20(19): 5737-5745
- URL: https://www.wjgnet.com/1007-9327/full/v20/i19/5737.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i19.5737