Risk factors for liver-related mortality in chronic hepatitis C patients: A deceased case-living control study

Table 3 Unadjusted univariate conditional logistic regression analysis of potential risk factors for chronic hepatitis C mortality n (%)

Variable	Cases (n = 144)	Controls (n = 576)	UOR (95%CI)	B	P value
Initial diagnostic stage
CHC	55 (38.19)	404 (70.14)	1.00 (Reference)	NA	NA
LC	60 (41.67)	152 (26.39)	3.03 (1.98-4.64)	1.11	0.000
HCC	29 (20.14)	20 (3.47)	13.19 (6.41-27.12)	2.58	0.000
HBsAg negativity	125 (86.81)	570 (98.96)	1.00 (Reference)	NA	NA
HBsAg positivity	19 (13.19)	6 (1.04)	22.99 (6.77-78.04)	3.14	0.000
Without diabetes	102 (70.83)	464 (80.56)	1.00 (Reference)	NA	NA
With diabetes	42 (29.17)	112 (19.44)	1.75 (1.14-2.67)	0.56	0.010
Without antiviral therapy	126 (88.89)	392 (73.78)	1.00 (Reference)	NA	NA
With antiviral therapy	16 (11.11)	151 (26.22)	0.32 (0.18-0.57)	-1.14	0.000
Without hypertension	99 (68.75)	452 (78.47)	1.00 (Reference)	NA	NA
With hypertension	45 (31.25)	124 (21.53)	1.65 (1.10-2.47)	0.5	0.015
Without alcohol consumption	92 (63.89)	419 (72.74)	1.00 (Reference)	NA	NA
With alcohol consumption	52 (36.11)	157 (27.26)	1.67 (1.08-2.59)	0.51	0.021
Anti-HBc negativity	48 (33.33)	263 (45.66)	1.00 (Reference)	NA	NA
Anti-HBc positivity	96 (66.67)	313 (54.34)	1.69 (1.15-2.48)	0.52	0.008
Without transfusion history	123 (85.42)	342 (59.37)	1.00 (Reference)	NA	NA
With transfusion history	21 (14.58)	234 (40.63)	NA	NA	0.060
Non-smoker	104 (72.22)	444 (77.08)	1.00 (Reference)	NA	NA
Ever smoker	40 (27.78)	132 (22.92)	NA	NA	0.193
Without family history of viral hepatitis	131 (90.97)	521 (90.45)	1.00 (Reference)	NA	NA
Family history of viral hepatitis	13 (9.03)	55 (9.55)	NA	NA	0.846

UOR: Unadjusted odds ratios; B: Regression coefficient; CHC: Chronic hepatitis C; LC: Liver cirrhosis; HCC: Hepatocellular carcinoma; NA: Not applicable; HBsAg: Hepatitis B surface antibody; Anti-HBc: Anti-hepatitis core antibody.