Original Article
Copyright ©2014 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2014; 20(18): 5474-5482
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5474
Table 2 Differential glycopattern in gastric ulcer and cancer according to the lectin microarray analysis based on data from 37 lectins giving significant signals
LectinSpecificityNormalized fluorescent intensity1
Ratio, P value
Gastric cancerGastric ulcer(C/U)
JacalinGalβ1-3GalNAcα-Ser/Thr(T) and GalNACα-Ser/Thr(Tn)0.49-P < 0.001
ECAGalβ-1,4GlcNAc0.72-P < 0.001
HHLPolymannose (α-1,3) and (α-1,6) linked mannose0.64-P < 0.001
WFAGalNAcα/β-1,3/6Gal0.64-P < 0.001
GSL-IIGlcNAc0.67-P < 0.001
MAL-IISia2-3Galβ1-4Glc (NAc)--/
PHA-EBisecting GlcNAc and biantennary N-glycans0.65-P < 0.001
PTL-IαGalNAc0.67-P < 0.001
SJATerminal in GalNAc and Gal0.120.380.32, P < 0.001
PNAGalβ1-3GalNAcα-Ser/Thr(T)0.080.220.36, P < 0.001
EELGalα1-3(Fucα1-2)Gal10.234.41, P < 0.001
AALFucα-1,6GlcNAc, Fucα-1,3LacNAc0.89-P < 0.001
LTLα-L-Fuc0.590.31/
MPLαGalNAc0.69-P < 0.001
LELPoly-LacNAc and (GlcNAc)n0.540.27/
GSL-IαGalNAc, αGal-0.03P < 0.001
DBAGalNAcα-Ser/Thr(Tn)0.40.2/
LCAα-Man and Fucα-1,6GlcNAc (core fucose)0.61-P < 0.001
RCA120Gal and GalNAc0.610.173.55, P < 0.001
STL(GlcNAc)n0.540.31/
BS-IαGal and αGalNAc0.12-P < 0.001
ConAα-Man (inhibited by presence of bisecting GlcNAc)0.130.11/
PTL-IIGal0.66-P < 0.001
DSAβ1-4GlcNAc and LacNAc0.7910.79, P < 0.001
SBATerminal GalNAc (especially GalNAcα1-3Gal)0.38-P < 0.001
VVAGalNAc and GalNAcα-Ser/Thr(Tn)0.45-P < 0.001
NPLPolymannose(α-1,6)linked mannose0.640.125.21, P < 0.001
PSAFucα-N-acetylchitobiose -man0.850.24.19, P < 0.001
ACAGalβ1-3GalNAcα-Ser/Thr(Tn)0.710.183.84, P < 0.001
WGATerminal GlcNAc and (GlcNAc)n0.35-P < 0.001
UEA-IFucoseα1-2Galβ1-4Glc(NAc)0.81-P < 0.001
PWMGlcNAc0.8-P < 0.001
MAL-IGalβ-1,4GlcNAc and Sia2-3Galβ1-4Glc(NAc)0.630.163.89, P < 0.001
GNA(α-1,3)Man0.780.099.1, P < 0.001
BPLGalβ1-3GalNAc0.67-P < 0.001
PHA-E+LTri-and tetra-antennary complex-type N-glycan0.92-P < 0.001
SNASia2-6Galβ1-4Glc(NAc)0.610.183.39, P < 0.001