Topic Highlight
Copyright ©2014 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2014; 20(18): 5442-5460
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5442
Table 2 Drug therapy for portopulmonary hypertension
DrugRoute of administrationMechanism of action
EpoprostenolIntravenousVasodilator, anti-platelet and anti-proliferative
AmbrisentanOrallySelective endothelin-A receptor antagonist
BosentanOrallyEndothelin-A and Endothelin B receptor antagonist
SildenafilOrallyPhosphodiesterase inhibitor
IloprostInhaledProstacyclin analogue