Pros and cons of liver transplantation in human immunodeficiency virus infected recipients

Table 3 Factors predictive of mortality and graft failure at multivariate analysis in human immunodeficiency virus/hepatitis C virus recipients of liver transplantation

Mortality	HR (95%CI), P value	Graft loss	HR (95%CI), P value
HIV infection[14,35]	2.3 (1.3–3.8), 0.0002	BMI < 21[35]	3.2 (1.3–7.7), 0.01
HCV genotype 1[14]	2.14 (1.24–3.41), 0.006	Donor age by decade[35]	1.3 (1.0–1.6), 0.04
Donor index risk[35]	3.03 (1.57–5.83), 0.001	HCV-positive donor[35]	2.5 (1.1–5.6), 0.03
		Combined kidney-lT[35]	3.8 (1.6–9.1), 0.003
		MELD score[14]	1.06 (1.01–1.11), 0.023
		Centers performing < 1 LT/yr[14]	2.82 (1.30–6.94), 0.009
		Treated acute rejection1[35]	2.0 (1.0–4.0), 0.06
		HIV infection[35]	1.9 (1.2–3.1), 0.01

¹In HIV-positive individuals with or without HCV. HCV: Hepatitis C virus; BMI: Body mass index; LT: Liver transplantation; HIV: Human immunodeficiency virus.