Neo-adjuvant therapy for hepatocellular carcinoma before liver transplantation: Where do we stand?

Table 1 Studies of external beam radiotherapy for hepatocellular carcinoma before liver transplant

Ref.	n	Medial dose (Gy)/fractions (n)	Tumor (n)	Size of tumor (cm)	Child C n (%)	Patients who failed previous LRT	Radiological CR/PR	Transplanted after EBRT	HCC recurrence after LT
Sandroussi et al[50]	10	33/6	2 (1-10)	6.3 (2.2-10.8)	1 (10)	5	0/7	5	0
Andolino et al[13]	60	48/3	1 (1-3)	3.1 (1.0-6.5)	0	23	18/24	23	2
Katz et al[14]	18	50/10	1 (1-2)	4.0 (1.2-6.5)	4 (22)	3	0/4	11	0
O'Connor et al[49]	10	51/3	1 (1-2)	3.4 (2.5-5.5)	1 (10)	4	NA	10	0

HCC: Hepatocellular carcinoma; LRT: Locoreginal therapy; CR: Complete response; PR: Partial response; EBRT: External beam radiotherapy; NA: Not available.