Histological healing favors lower risk of colon carcinoma in extensive ulcerative colitis

Table 1 Demographics, decades of surveillance, and probable influence of advances in drug therapy

Characteristics	Group 1CA/HGD	Group 2Non-CA/HGD
n = 68	20	48
Gender (% female)	50%	46%
Age at diagnosis (yr), range	27.3 (8-51)	25 (6-61)
Disease duration (yr), range	27.3 (12-54)	29.6 (16-48)
Treatment with 6 MP/IFX
Subjects/decades of diagnosis of UC	Subjects received1	Subjects received2
1930-1949	1	0
1950-1959	1	0
1960-1969	7	5
1970-1979	9	17
1980-1989	2	16
1990-1999	0	10

¹1970-1989, 6-mercaptopurine (6MP) = 55%, infliximab (IFX) = 0%;

²1960-1999, 6MP = 79%; 1980-1999, IFX = 27%. CA: Carcinoma; HGD: High-grade dysplasia; UC: Ulcerative colitis.