New serological markers in pediatric patients with inflammatory bowel disease

doi:10.3748/wjg.v20.i17.4873

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May 7, 2014 (publication date) through Jan 20, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 7, 2014; 20(17): 4873-4882
Published online May 7, 2014. doi: 10.3748/wjg.v20.i17.4873

Table 3 Association of the new serologic markers with phenotype in pediatric Crohn’s disease

Marker	CD phenotype	Ref.
Anti-OmpC Anti-CBir1 Anti-I2 ASCA	Complicated disease behavior CD-related surgery	[10,26]
gASCA	Early disease onset	[30¹,31]
	Ileal disease location
	Complicated disease behavior Perianal disease
	CD-related surgery
ACCA	Complicated disease behavior CD-related surgery	[30]¹
ALCA	Ileal disease location	[30¹,31]
ALCA	Complicated disease behavior CD-related surgery	[30¹,31]
AMCA	Complicated disease behavior perianal disease	[30¹,31]
Anti-L	Ileal disease location	[30¹,31]
	Complicated disease behavior Perianal disease
	CD-related surgery
Anti-C	Complicated disease behavior Perianal disease	[30]¹
Anti-C	CD-related surgery	[30]¹
Anti-GP2 with ASCA	Early disease onset	[45]¹
	Ileal location
	Complicated behavior
	Perianal disease

¹Mixed pediatric and adult cohort. Anti-OmpC: Antibodies against outer membrane porin C of Escherichia coli; Anti-CBir1: Antibodies against bacterial flagellin CBir1; Anti-I2: Antibodies against the Pseudomonas-associated sequence; ASCA: Antibodies against Saccharomyces cerevisiae; AMCA: Anti-mannobioside carbohydrate antibodies; ALCA: Anti-laminaribioside carbohydrate antibodies; ACCA: Anti-chitobioside carbohydrate antibodies; Anti-L: Anti-laminarin carbohydrate antibodies; Anti-C: Anti-chitin carbohydrate antibodies; Anti-GP2: Antibodies against glycoprotein 2.

Citation: Kovács M, Müller KE, Papp M, Lakatos PL, Csöndes M, Veres G. New serological markers in pediatric patients with inflammatory bowel disease. World J Gastroenterol 2014; 20(17): 4873-4882
URL: https://www.wjgnet.com/1007-9327/full/v20/i17/4873.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i17.4873