Combined probiotic bacteria promotes intestinal epithelial barrier function in interleukin-10-gene-deficient mice

Figure 4 Bifico ameliorated the ultrastructure of colonic epithelium in interleukin-10 gene-deficient mice. A: Intercellular tight junctions (indicated by the white arrows) and normal ultrastructure in colonic epithelium of WT (scale bar = 2000 nm); B: Intercellular tight junctions (indicated by the white arrows) and normal ultrastructure in colonic epithelium of Bifico treated WT mice (scale bar = 1000 nm); C: Tight junctions (indicated by the white arrows) and microvilli, increased intercellular gap, and abnormal ultrastructure of epithelial cells in the colonic epithelium of IL-10 KO mice (scale bar = 1000 nm); D: Partly recovered intercellular tight junctions (indicated by the white arrows) and microvilli in colonic epithelium of Bifico treated IL-10 KO mice (scale bar = 1000 nm).