Role of human epidermal growth factor receptor 2 in gastric cancer: Biological and pharmacological aspects

doi:10.3748/wjg.v20.i16.4526

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Apr 28, 2014 (publication date) through Nov 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2014; 20(16): 4526-4535
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4526

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Figure 4 Human epidermal growth factor receptor 2 testing algorithm with fluorescence in situ hybridization reflex testing for both immunohistochemistry 2+ and immunohistochemistry 3+. This testing algorithm was recommended by the United States Food and Drug Administration in relation to approval of trastuzumab for advanced gastric cancer. FISH: Fluorescence in situ hybridization; IHC: Immunohistochemistry.

Citation: Jørgensen JT. Role of human epidermal growth factor receptor 2 in gastric cancer: Biological and pharmacological aspects. World J Gastroenterol 2014; 20(16): 4526-4535
URL: https://www.wjgnet.com/1007-9327/full/v20/i16/4526.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i16.4526