Hepatoprotective effect of Cichorium intybus L., a traditional Uighur medicine, against carbon tetrachloride-induced hepatic fibrosis in rats

doi:10.3748/wjg.v20.i16.4753

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Apr 28, 2014 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2014; 20(16): 4753-4760
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4753

Table 4 Effect of a Cichorium intybus L. extract on liver glutathione, superoxide dismutase and malondialdehyde levels in rats

Treatment	GSH	MDA	SOD
Treatment	(mg/gprot)	(nmol/mgprot)	(U/mgprot)
Control	6.58 ± 0.62	1.93 ± 0.18	334.12 ± 13.75
CCl₄	2.52 ± 0.69^b	4.01 ± 1.00^b	193.58 ± 20.76^b
6 g/kg CIE + CCl₄	2.93 ± 0.99	3.73 ± 0.61	223.23 ± 38.20^d
18 g/kg CIE + CCl₄	3.03 ± 0.76	3.25 ± 0.73^d	241.29 ± 40.21^d
54 g/kg CIE + CCl₄	3.11 ± 0.81	2.76 ± 0.51^d	269.98 ± 33.77^d
FFBJRGP (780 mg/kg)	4.44 ± 1.28^d	2.04 ± 0.70^d	274.43 ± 32.62^d

Values are expressed as the mean ± SD, n = 12. Compared with control group,

^bP < 0.01; Compared with CCl₄-exposed group,

^dP < 0.01. GSH: Glutathione; MDA: Malondialdehyde; SOD: Superoxide dismutase; CIE: Cichorium intybus L. extract; FFBJRGP: Fu Fang Bie Jia Ruan Gan Pian.

Citation: Li GY, Gao HY, Huang J, Lu J, Gu JK, Wang JH. Hepatoprotective effect of Cichorium intybus L., a traditional Uighur medicine, against carbon tetrachloride-induced hepatic fibrosis in rats. World J Gastroenterol 2014; 20(16): 4753-4760
URL: https://www.wjgnet.com/1007-9327/full/v20/i16/4753.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i16.4753